| Twin Eagle - Revenge Joe's Brother (USA) | |
| Twin Eagle - Shuang Ying (Asia) (Unl) (Famicom) | |
| Twin Eagle (Asia) (Unl) (NES) | |
| TwinBee (Japan) | |
| TwinBee 3 - Poko Poko Dai Maou (Japan) | |
| TwinBee 3 - Poko Poko Dai Maou (Japan) (Beta) | |
| TwinBee 3 - Poko Poko Dai Maou (Japan) [En by Demiforce+Stardust Crusaders v1.0] (~TwinBee 3 - The Aimless Demon King) | |
| U.S. Championship V'Ball (Japan) | |
| U.S. Championship V'Ball (Japan) (Beta) | |
| Uchuu Keibitai SDF (Japan) | |
| Uchuusen - Cosmo Carrier (Japan) | |
| Ufouria - The Saga (Europe) | |
| Ufouria - The Saga (Europe) (Beta) | |
| Ultima - Exodus (Japan) | |
| Ultima - Exodus (USA) | |
| Ultima - Quest of the Avatar (USA) | |
| Ultima - Seija heno Michi (Japan) | |
| Ultima - Warriors of Destiny (USA) | |
| Ultimate Air Combat (Europe) (En,Fr,De) | |
| Ultimate Air Combat (Europe) (En,Fr,De) (Beta) | |
| Ultimate Air Combat (USA) | |
| Ultimate Basketball (USA) | |
| Ultimate League Soccer (Italy) (Unl) | |
| Ultimate League Soccer (USA) (Unl) | |
| Ultimate Mortal Kombat 3 | |
| Ultimate Stuntman, The (USA) (Unl) | |
| Ultraman Club - Kaijuu Dai Kessen!! (Japan) | |
| Ultraman Club 2 - Kaettekita Ultraman Club (Japan) | |
| Ultraman Club 3 (Japan) | |
| Uncanny X-Men, The (USA) | |
| Uncharted Waters (USA) | |
| Uncle Mario Bros. | |
| Uninvited (USA) | |
| Untouchables, The (Japan) | |
| Untouchables, The (USA) | |
| Untouchables, The (USA) (Rev A) | |
| Untouchables, The (USA) (Rev B) | |
| Urban Champion (World) | |
| Urusei Yatsura - Lum no Wedding Bell (Japan) | |
| Urusei Yatsura - Lum no Wedding Bell (Japan) [En by Stardust Crusaders v1.0] (~Urusei Yatsura - Lum's Wedding Bell) | |
| USA Ice Hockey in FC (Japan) | |
| Ushio to Tora - Shinen no Daiyou (Japan) | |
| Utsurun Desu (Japan) | |
| Valis - The Fantastic Soldier (Japan) | |
| Valis - The Fantastic Soldier (Japan) [En by Satsu+Sliver X v1.0] (~Valis - The Fantasm Soldier) | |
| Valis - The Fantastic Soldier (Japan) [En+Hack by Satsu+Sliver X v1.01] (~Valis Plus Plus - The Fantasm Soldier) | |
| Valkyrie no Bouken - Toki no Kagi Densetsu (Japan) | |
| Valkyrie no Bouken - Toki no Kagi Densetsu (Japan) [En by DvD Rev A] (~Valkyrie's Adventure - Legend of the Time Key) | |
| Vegas Connection - Casino Kara Ai wo Komete (Japan) | |
| Vegas Dream (USA) | |