| Sabre Wulf (E)(Rising Sun) | |
| Sabre Wulf (U)(Independent) | |
| Sabrina | |
| The Teenage Witch - Potion Commotion (E)(LightForce) | |
| Sabrina The Teenage Witch - Potion Commotion (U)(Eurasia) | |
| Sakura Momoko no Ukiuki Carnival (J)(Independent) | |
| Salt Lake 2002 (E)(Independent) | |
| Salt Lake 2002 (U)(Mode7) | |
| Samurai Deeper Kyo (J)(Eurasia) | |
| Samurai Deeper Kyo (U)(Sir VG) | |
| Samurai Evolution - Oukoku Geist (J)(Patience) | |
| Samurai Jack - The Amulet of Time (U)(Mode7) | |
| San Goku Shi (C)(Independent) | |
| San Goku Shi (J)(Cezar) | |
| Sangokushi Eiketsuden (J)(RisingCaravan) | |
| Sangokushi Koumeiden (J)(RisingCaravan) | |
| Sanrio Puroland All Characters (J)(Rising Sun) | |
| Sansara Saga 1x2 (J)(Lame) | |
| Santa Claus Jr (E)(Eurasia) | |
| Santa Claus Saves the Earth (E)(Eurasia) | |
| Scan Hunter (J)(Evasion) | |
| Scooby-Doo - Das Spiel zum Film (G)(Rising Sun) | |
| Scooby-Doo - Mystery Mayhem (E)(Independent) | |
| Scooby-Doo - Mystery Mayhem (U)(Hyperion) | |
| Scooby-Doo - The Motion Picture (E)(Independent) | |
| Scooby-Doo - The Motion Picture (F)(Patience) | |
| Scooby-Doo - The Motion Picture (S)(Independent) | |
| Scooby-Doo - The Motion Picture (U)(Mode7) | |
| Scooby-Doo - Unmasked (U)(Trashman) | |
| Scooby-Doo 2 - Monster Unleashed (E)(Rising Sun) | |
| Scooby-Doo 2 - Monsters Unleashed (U)(Hyperion) | |
| Scooby-Doo and the Cyber Chase (E)(Patience) | |
| Scooby-Doo and the Cyber Chase (U)(Venom) | |
| Scooby-Doo Gamepack (E)(Independent) | |
| Scooby-Doo Gamepack (U)(Eternity) | |
| Scooby-Doo! - Unmasked (E)(Independent) | |
| Scourge The Hedgehog Over Emerl '[Spanish]' | |
| Scrabble (E)(Lightforce) | |
| Scrabble Blast! (U)(TrashMan) | |
| Scrabble Scramble (E)(Rising Sun) | |
| Scrabble Scramble (E)(Sir VG) | |
| Screw Breaker - Goushin Dorirurero (J)(WRG) | |
| Scurge Hive (E)(Rising Sun) | |
| Scurge Hive (U)(Rising Sun) | |
| SD Gundam Force (J)(Independent) | |
| SD Gundam Force (U)(Rising Sun) | |
| SD Gundam G Generation Advance (J)(Independent) | |
| Sea Trader - Rise of Taipan (U)(Eurasia) | |
| Sea World - Shamu's Deep Sea Adventure (U)(Trashman) | |
| Sega Arcade Gallery (E)(Patience) | |
| Sega Arcade Gallery (U)(TrashMan) | |