| SimCity 2000 (USA) | |
| SimCity Jr. (Japan) | |
| SimEarth - The Living Planet (Japan) (Rev 0A) | |
| SimEarth - The Living Planet (USA) | |
| Simpsons, The - Bart no Fushigi na Yume no Daibouken (Japan) | |
| Simpsons, The - Bart's Nightmare (Europe) | |
| Simpsons, The - Bart's Nightmare (USA) | |
| Simulation Pro Yakyuu (Japan) | |
| Sink or Swim (Europe) | |
| Sink or Swim (USA) | |
| Ski Paradise with Snowboard (Japan) | |
| Skuljagger - Revolt of the Westicans (USA) | |
| Skuljagger - Revolt of the Westicans (USA) (Beta) | |
| Sky Mission (Japan) | |
| Skyblazer (Europe) | |
| Skyblazer (USA) | |
| Skyblazer (USA) (Beta1) | |
| Skyblazer (USA) (Beta2) | |
| Slap Stick (Japan) | |
| Slayers (Japan) | |
| Slayers (Japan) [En by Filler v0.20] (Incomplete) | |
| SM Choukyoushi Hitomi - Bangai Hen (Japan) (Unl) | |
| SM Choukyoushi Hitomi - Bangai Hen 2 - Maki no Love Love Panic (Japan) (Unl) | |
| SM Choukyoushi Hitomi - Test Version (Japan) (Unl) | |
| SM Choukyoushi Hitomi (Japan) (Unl) | |
| SM Choukyoushi Hitomi Vol. 2 - Trial Version (Japan) (Unl) | |
| SM Choukyoushi Hitomi Vol. 2 (Japan) (Unl) | |
| SM Choukyoushi Hitomi Vol. 2 Remix (Japan) (Unl) | |
| SM Choukyoushi Hitomi Vol. 3 - Test Version (Japan) (Unl) | |
| SM Choukyoushi Hitomi Vol. 3 (Japan) (Unl) [0810] | |
| SM Choukyoushi Hitomi Vol. 3 (Japan) (Unl) [1087] | |
| Smart Ball (USA) | |
| Smash T.V. (Japan) | |
| Smash Tennis (Europe) | |
| Smash Tennis (Europe) (Beta) | |
| SMPRGRevolutionV1.1a | |
| Smurfs 2, The (Europe) (En,Fr,De,Es) | |
| Smurfs, The (Europe) (En,Fr,De,Es,It) | |
| SMW The Crown Tale by bandicoot | |
| Snoopy Concert (Japan) | |
| Snoopy Concert (Japan) [En by Aeon Genesis v1.0] | |
| Snow White in Happily Ever After (USA) | |
| So 2 Mice Walk Into a Bar... by S.N.N., idol | |
| Soccer Kid (Europe) (En,Fr,De,Es,It) | |
| Soccer Kid (Japan) | |
| Soccer Kid (Japan) (Beta) | |
| Soccer Shootout (Europe) | |
| Soldiers of Fortune (USA) | |
| Solid Runner (Japan) | |
| Solstice II (Japan) | |