| C2 Sonic 1 | |
| C2 Sonic 2 | |
| Cadash (USA, Asia) | |
| Caesar no Yabou (Japan) | |
| Caesar no Yabou II (Japan) | |
| Caesars Palace (USA) | |
| Cal Ripken Jr. Baseball (USA) | |
| Caliber .50 (USA) | |
| California Games (USA, Europe) | |
| Cannon Fodder (Europe) | |
| Captain America and the Avengers (Europe) | |
| Captain America and the Avengers (USA) | |
| Captain America and the Avengers (USA) (Beta) | |
| Captain Planet and the Planeteers (Europe) | |
| Captain Planet and the Planeteers (USA) | |
| Castle of Illusion - Fushigi no Oshiro Daibouken (Japan) | |
| Castle of Illusion Starring Mickey Mouse (USA, Europe) | |
| Castlevania - Bloodlines (USA) | |
| Castlevania - The New Generation (Europe) | |
| Castlevania - The New Generation (Europe) (Beta) | |
| Castlevania Bloodlines Enhanced Colors | |
| Centurion - Defender of Rom | |
| e (USA, Europe) | |
| Chakan (USA, Europe) | |
| Chameleon Kid (Japan) | |
| Champions World Class Soccer (World) (En,Fr,De,Es) | |
| Championship Bowling (USA) | |
| Championship Pool (USA) | |
| Championship Pro-Am (USA) | |
| Chaoji Dafuweng (China) (Unl) | |
| Chaos Engine 2, The (Europe) (Proto) | |
| Chaos Engine, The (Europe) | |
| Chase H.Q. II (USA) | |
| Chavez II (USA) | |
| Cheese Cat-Astrophe Starring Speedy Gonzales (Europe) | |
| Chelnov (Japan) | |
| Chester Cheetah - Too Cool to Fool (USA) | |
| Chester Cheetah - Wild Wild Quest (USA) | |
| Chi Chi's Pro Challenge Golf (USA) | |
| Chibi Maruko-chan - Wakuwaku Shopping (Japan) | |
| Chiki Chiki Boys (Japan) | |
| Chiki Chiki Boys (USA, Europe) | |
| Chip 'n Dale Rescue Rangers (Unl) | |
| Chip 'n Dale Rescue Rangers 2 (Unl) | |
| Chou Kyuukai Miracle Nine (Japan) | |
| Chou Touryuu Retsuden Dino Land (Japan) | |
| Chrome Metal Sonic The Hedgehog | |
| Chrome Metal Sonic The Hedgehog 2 | |
| Chuck Rock (Europe) | |
| Chuck Rock (USA) | |
| Chuck Rock II - Son of Chuck (Europe) | |