| R.B.I. Baseball 3 (USA) | |
| R.B.I. Baseball 4 (USA) | |
| R.B.I. Baseball 93 (USA) | |
| R.B.I. Baseball 94 (USA, Europe) | |
| Race Drivin' (USA) | |
| Radical Rex (Europe) | |
| Radical Rex (USA) | |
| Ragnacenty (Korea) | |
| Raiden Densetsu ~ Raiden Trad (Japan, USA) | |
| Rainbow Islands Extra (Japan) | |
| Rambo III (World) | |
| Rambo III (World) (v1.1) | |
| Rampart (USA) | |
| Ranger-X (Europe) | |
| Ranger-X (USA) | |
| Ransei no Hasha (Japan) | |
| Rastan Saga II (Japan) | |
| Rastan Saga II (USA) | |
| Ray in Sonic 1 | |
| Red Sonic 1 Game Gear Edition (2024) | |
| Red Sonic in Sonic 2 | |
| Red Sonic The Hedgehog Halloween | |
| Red Zone (USA, Eur | |
| ope) | |
| Reimu in Streets of Rage 2 | |
| Ren & Stimpy Show Presents Stimpy's Invention, The (Europe) | |
| Ren & Stimpy Show Presents Stimpy's Invention, The (USA) | |
| Ren & Stimpy Show Presents Stimpy's Invention, The (USA) (Beta) | |
| Rent a Hero (Japan) | |
| Resq (Europe) (Proto) | |
| Revenge of Shinobi, The (USA, Europe) | |
| Revenge of Shinobi, The (USA, Europe) (Rev A) | |
| Revenge of Shinobi, The (USA, Europe) (Rev B) | |
| Revolution X (USA, Europe) | |
| Richard Scarry's BusyTown (USA) | |
| Rings of Power (USA, Europe) | |
| Rise of the Robots (Europe) | |
| Risk (USA) | |
| Risky Woods (USA, Europe) | |
| Ristar - The Shooting Star (Japan) | |
| Ristar (Aug 12, 1994 prototype) | |
| Ristar (Aug 26, 1994 prototype) | |
| Ristar (Jul 1, 1994 prototype) | |
| Ristar (Jul 18, 1994 prototype) | |
| Ristar (USA, Europe) (August 1994) | |
| Ristar (USA, Europe) (September 1994) | |
| Road Rash (USA, Europe) | |
| Road Rash 3 (USA, Europe) | |
| Road Rash 3 (USA) (Alpha) | |
| Road Rash II (Japan) | |
| Road Rash II (USA, Europe) | |